ZynAddSubFX

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Screen dump: 
ZynAddSubFX's voice parameter window

ZynAddSubFX is a open source software synthesizer capable of creating a countless number of instruments. It is feature rich and has a large number of parameters. It includes three hybrid synth engines that combine additive, subtractive, fourier and other synthesis methods. ZynAddSubFX is available as a standalone, LV2 and DSSI plugin.